Ah you mean more resistance in terms of the extra loading from the greater inefficiency of the rear wheel drive line compared to the front, so more losses and therefore more engine load to sustain same vehicle speed and acceleration. I understand what you mean now but I can't imagine it making much of a difference in terms of cooling.
The front wheel drive pumps have an extra impellow blade, I won't pretend to know if this has much of an effect hence my careful wording.
Blocking the heater line is a good idea, otherwise you have a pretty serious compromise on your cooling system.
All this said 4age engines just don't run very hot usually. I ran my 20v for many years without a fan and a Hyundai radiator.